HDAC9 antibody

Catalog No. ABIN6568596

The Rabbit Polyclonal anti-HDAC9 antibody has been validated for WB. It is suitable to detect HDAC9 in samples from Human, Rat and Mouse.

Quick Overview for HDAC9 antibody (ABIN6568596)

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HDAC9 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human HDAC9

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HDAC9

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Alternative Name: Histone deacetylase 9

Background:

Synonyms: Histone deacetylase 9,HD9,Histone deacetylase 7B,HD7,HD7b,Histone deacetylase-related protein,MEF2-interacting transcription repressor MITR,HDAC9,HDAC7,HDAC7B,HDRP,KIAA0744,MITR

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Molecular Weight:

Observed_MW: 97kDa

Calculated_MW: 57-65kDa/97-117kDa

Gene ID: 9734

UniProt: Q9UKV0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development